Friday, August 8, 2025
Orodental anomalies encompass conditions affecting tooth number, morphology, and eruption patterns, with supernumerary teeth being particularly significant due to their potential to disrupt occlusion, eruption, and alignment. This study aimed to identify and characterize these anomalies in a Thai population using panoramic radiographs. Data analysis revealed 56.0% prevalence of orodental anomalies, with tooth impaction being the most common (37.4%), followed by periapical radiolucency (13.5%) and hypodontia (5.1%). Supernumerary teeth were identified in 1.2% of cases, most commonly as single (76.7%), unerupted (70%), and supplemental-type teeth (76.7%). Significant associations were found with microdontia (p < 0.001) and tooth impaction (p < 0.002), but these associations were not statistically significant when adjusted for gender. The study identified a range of orodental anomalies, highlighting the need for thorough radiographic evaluation in cases presenting with eruption disturbances or tooth size anomalies. These findings underscore the importance of incorporating anomaly screening in routine dental radiography and warrant multicenter investigations for broader generalizability. Orodental anomalies, including supernumerary teeth, are associated with various complications, and their prevalence varies by population and age. The study also focused on characterizing supernumerary teeth, which were significantly associated with other anomalies such as impaction and microdontia in bivariate analysis, though this association was not confirmed by logistic regression. Despite this, the observed co-occurrence highlights the need for comprehensive radiographic assessment in these conditions. The study aimed to investigate orodental anomalies in a Thai population using panoramic radiographs, providing a broader adult dataset and including less commonly analyzed locations. A retrospective observational study identified and characterized supernumerary teeth, including their clinical and radiographic features. The findings emphasize the necessity of thorough radiographic evaluation and suggest the need for further research on these conditions. The study also highlighted the importance of systematic assessment and standardization in dental radiography.
Reference: Radiographic evaluation of orodental anomalies in a Thai population: prevalence, supernumerary teeth characteristics, and associated factorsLabels: BMC Oral Health
0 CommentsThursday, August 7, 2025
This study evaluates the effects of polyvinylpyrrolidone sodium hyaluronate gel (Gelclair®) on palatal wound healing, pain, and bleeding following free gingival graft surgery (FGG). Thirty-two patients underwent FGG and were randomly assigned to two groups: the test group received Gelclair® and chlorhexidine mouthwash, while the control group received only chlorhexidine. Patients were assessed at first, third, seventh, fourteenth, and twenty-eighth postoperative days using the Visual Analog Scale (VAS), Wound Healing Index (WHI), hydrogen peroxide (H₂O₂) bubbling scores, and bleeding situations. Friedman and Wilcoxon signed-rank tests were used for repeated measures and between-group comparisons. H₂O₂ test values decreased over time in both groups, with significant differences observed in H₂O₂ test values on days 7, 14, and 28 compared to the control group. WHI values increased similarly, showing significant improvements in both groups. VAS pain, chewing, and burning scores were also significantly lower in the test group on days 1, 3, 7, and 14 compared to the control group. Control groups reported higher bleeding rates on day 1 compared to the test group (p < 0.001). The study suggests that Gelclair® promotes wound healing and reduces discomfort and bleeding in the palatal donor area after FGG. NCT06610331; Retrospectively registered on 23/09/2024. Free gingival grafts (FGGs) are often used in periodontal plastic surgery to address gingival and peri-implant soft tissue defects and restore keratinized gingiva [1]. FGGs are considered the gold standard for treating gingival recession [2], augmenting peri-implant soft tissue, and preserving the alveolar ridge [3, 4]. Due to its anatomical advantages and optimal tissue thickness, the palatal keratinized mucosa is recommended as the ideal donor site for FGG [5]. After FGG surgery, the palatal donor site undergoes secondary wound healing [6]. One of the major postoperative challenges for patients is the morbidity associated with the palatal donor site [7]. Pain is the most common postoperative complication, with some patients recalling this discomfort even a decade after the procedure [8]. Other potential palatal complications include prolonged bleeding, necrosis, infection, and delayed wound healing, often due to injury to the greater palatine artery during surgery [7]. Numerous clinical studies have focused on improving palatal wound healing and reducing patient discomfort [9, 10, 11, 12]. Hyaluronic acid (HA) is a connective tissue component found in the periodontal ligament and gingival tissues, exhibiting bacteriostatic, anti-inflammatory, and antioxidant properties [13]. With its remarkable moisturizing, retention, and viscoelastic capacities, HA contributes to essential structural, rheological, physiological, and biological functions. Due to its anti-immunogenic and non-toxic characteristics that support periodontal wound healing, it is widely used in reconstructive periodontal soft tissue surgery [14]. An in vitro study demonstrated that the film form of HA enhances adhesion upon contact with water, facilitating its penetration into tissues and supporting the prolonged functional effect of HA within the tissue [15]. Supporting this finding, an in vivo animal study showed that the HA film structure promoted palatal wound healing both clinically and histologically in experimentally induced palatal wounds in rats [16]. Gelclair® is a film form bioadhesive oral gel commonly used to treat painful oral lesions. This viscous gel contains polyvinylpyrrolidone (PVP), sodium hyaluronate, and glycyrrhetinic acid. The chemical structure of PVP allows it to adhere to mucosal surfaces and form a protective film. Sodium hyaluronate which is a type of HA salt; improves tissue lubrication and hydration due to its high water-holding capacity and viscoelastic properties. Glycyrrhetinic acid supports wound healing through its anti-inflammatory effects. Together, these three components in Gelclair® provide hydration and lubrication to damaged tissues in the oral cavity and protect nerve endings from physical stimuli [17].
Reference: The effect of Polyvinylpyrrolidone-Sodium hyaluronate gel on palatal wound healing: a randomized controlled clinical trialLabels: BMC Oral Health
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The World Health Organization (WHO) has confirmed that Kenya has eliminated human African trypanosomiasis (HAT) or sleeping sickness as a public health problem, making it the tenth country to achieve this milestone. HAT, a second-neglected tropical disease, was already considered eliminated in 2018 with Guinea worm disease, and Kenya is now free of the rhodesiense form of the disease, which is present in eastern and southern Africa. Dr. Aden Duale, Kenya’s Cabinet Secretary for Health, highlighted this achievement as a significant step toward Africa’s elimination of neglected tropical diseases. The disease, caused by Trypanosoma brucei, is transmitted by tsetse flies and affects rural populations involved in agriculture, fishing, and animal husbandry. Kenya’s efforts, including training health workers and strengthening surveillance in 12 health facilities, have led to the elimination of HAT. The country has also improved monitoring of tsetse flies and trypanosomiasis, supported by the national veterinary health authorities and the Kenya Tsetse and Trypanosomiasis Eradication Council. The WHO continues to support the elimination program and maintain resources for post-validation surveillance.
Reference: Kenya achieves elimination of human African trypanosomiasis or sleeping sickness as a public health problemLabels: WHO
0 CommentsWednesday, August 6, 2025
Washington DC, USA, August 7, 2025 – Barbados is advancing its industrial policy to boost local production of medicines and health technologies by enhancing its national regulatory framework. The country, supported by the Pan American Health Organization (PAHO/WHO), is conducting an assisted self-benchmarking exercise using the World Health Organization’s (WHO) Global Benchmarking Tool (GBT), alongside a clinical trials training webinar. A PAHO Medicines and Health Technologies (IMT) team collaborates with Barbados to align regulatory practices with international standards, including reviewing functions like marketing authorization and pharmacovigilance. The GBT identifies strengths and areas for improvement in regulatory functions, supporting the development of institutional roadmaps for strengthening regulatory systems. During the mission, PAHO works with Barbados’ regulators and stakeholders to address clinical trial oversight, emphasizing the roles of ethics committees. A high-level meeting led by Minister Dr. The Most Honourable Jerome Walcott discussed next steps to implement the national roadmap and expand access to health technologies. Barbados continues to lead in the Caribbean, prioritizing regulatory excellence and equitable health product access. PAHO remains a key partner, providing long-term support to the Government of Barbados in building resilient health systems. This initiative is part of PAHO’s broader effort to strengthen national regulatory systems, supporting public health priorities in the Region of the Americas. Strong regulatory systems ensure product safety, support local production, and enhance preparedness for health emergencies.
Reference: Barbados Advances Regulatory System with PAHO Support to Boost Local Health Production CapacityLabels: PAHO
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Barbados hosted its second hybrid community mental health conversation on 30th July 2025 to update the public on the new Mental Health Act. Approximately 70 in-person attendees and 50 online joined the event, which included a young woman sharing her personal journey through primary school and bullying, highlighting the challenges she faced and the lack of support available. The session emphasized the new Bill's amendments, such as including children, parents, and emergency care. The presentation also highlighted services like mental health services at clinics and school programs. A young person from a psychiatric hospital suggested a mental health identification card to assist former patients, while another raised training needs for first responders. They were informed that doctors can help adjust medications if patients have adverse effects. The session also provided information on the patient's role and support, with the hearing impaired receiving interpreters. This event, part of the Ministry of Health and Wellness, offered a forum for sharing views, concerns, and suggestions.
Reference: Second Community Conversation hosted as part of Mental Health Reform in BarbadosLabels: PAHO
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Barbados hosted its second hybrid community mental health conversation on 30th July 2025 to familiarize the public with the draft Mental Health Act during the "Mind Yuh Mind" event held at Princess Margaret Secondary School. Approximately 70 in-person attendees and 50 online joined, creating a lively discussion. A young woman shared her personal journey from primary school dealing with learning challenges and bullying, highlighting the emotional toll these experiences had on her mental health and the limited support available. The session set the stage for the Mental Health Commission to outline changes to the Act, including provisions for children's rights, parents' rights, and emergency care. The Commission emphasized the need to include more trained staff, expanded support for non-mental health professionals, and community-based resources. A former patient noted the importance of a mental health identification card for former patients seeking employment, while a first responder's suggestion for training in emergency response was acknowledged. Another participant discussed medication side effects and emphasized the role of healthcare providers in managing these. The session highlighted that the new Bill addresses patient rights and their involvement in care plans, while the Mental Health Tribunal can intervene in abuse cases, and interpreter services for hearing-impaired individuals. This event was part of the Ministry of Health and Wellness' efforts to engage the public in understanding and participating in the mental health reforms.
Reference: Second Community Conversation hosted as part of Mental Health ReformLabels: PAHO
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GEORGETOWN, GUYANA – 7 AUGUST 2025 - In a brightly lit training room in Georgetown, healthcare workers from Guyana gathered to launch the 2025 Mass Drug Administration (MDA) training, a collaboration between the Ministry of Health and the Pan American Health Organization (PAHO/WHO). This initiative marks a significant step in Guyana’s journey to eliminate lymphatic filariasis, a disease that has burdened communities for nearly two centuries. The campaign, which aims to eliminate five neglected tropical diseases, emphasizes community involvement and health empowerment. With the IDA drug regimen combining Ivermectin, DiethylCarbamazine (DEC), and Albendazole, eight out of ten regions are free of the disease. Directly Observed Therapy (DOT) ensures medication compliance and trust-building by involving health workers in the process. Health workers are trained not only to administer drugs but also to educate, dispel myths, and lead by example. This approach fosters confidence in the community, ensuring accessibility to treatment. The campaign's success lies in its focus on dignity, opportunity, and social inclusion, empowering individuals to work, care for their families, and participate fully in society.
Reference: Guyana’s Fight Against Lymphatic Filariasis: A Story of Hope, Leadership, and CommunityLabels: PAHO
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